Are you just replacing the speakers and keeping the stock radio, or is this part of the new HU you've been posting about looking for.
In a C5Z the rears are 5.25", if you keep them functional that's pretty much what you're stuck with.
Front 'twiddlers' are 3.5", but there is also a self powered 'sub' type speaker in each door that's 8". The sub can't really be replaced with an aftermarket equivalent.
What most people do is remove the sub/twiddler assembly and put in a 6.5" coax or component set on custom (or self made) plates, then add a sub in the trunk. In a C5 the center tub is perfect for a stealth sub or bazooka type tube.
If you just want to improve the sound of the stock system, new 3.5" speakers in the doors will do fine. Polk db351 and Boston Acoustic S35 are popular, but any 4 ohm speaker will do.