If you want to maintain RAP with your new HU you need to buy something like the
Accessory Valet
If you just want the radio to turn on/off with the ignition (or key in ACC) then the easiest thing to do is use the YELLOW wire in the passenger footwell as the trigger wire to turn on the new HU. The ORANGE wire is constant +12V, and the BLACK wire is the ground. They are fused, so you should be able to safely use them to power and trigger a HU, but if you install an additional external amp you'd want to wire the constant to the battery through an appropriate fuse.
I don't recall what fuse 22 is, but it sounds like it isn't doing what you want it to.
From your other posts it looks like you're putting in a new HU and using the stock amps/speakers. Right?
What adapter did you use?